Overexpression of GATA-3 in T Cells Accelerates Dextran Sulfate Sodium-Induced Colitis
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چکیده
منابع مشابه
Overexpression of GATA-3 in T Cells Accelerates Dextran Sulfate Sodium-Induced Colitis
Ulcerative colitis (UC) is an inflammatory bowel disease, and its pathogenesis includes genetic, environmental, and immunological factors, such as T helper cells and their secreted cytokines. T helper cells are classified as Th1, Th2, and Th17 cells. However, it is unclear which T helper cells are important in UC. Dextran sulfate sodium (DSS)-induced colitis is a commonly used model of UC. In t...
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Ulcerative colitis (UC) is an inflammatory bowel disease, and its pathogenesis involves a variety of genetic, environmental, and immunological factors such as T helper cells and their secreted cytokines. B and T lymphocyte attenuator (BTLA) is an immunoregulatory receptor that has a strong suppressive effect on T-cell function. However the role of BTLA in UC remains poorly understood. Here we d...
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BACKGROUND AND AIMS Probiotic properties of Enterococcus strains have been reported previously. In this study, we investigated the effects of Enterococcus (E.) durans TN-3 on the development of dextran sulfate sodium (DSS) colitis. METHODS BALB/c mice were fed with 4.0% DSS in normal chow. Administration of TN-3 (10mg/day) was initiated 7days before the start of DSS feeding. Mucosal cytokine ...
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ژورنال
عنوان ژورنال: Experimental Animals
سال: 2014
ISSN: 1341-1357,1881-7122
DOI: 10.1538/expanim.63.133